Portfolio

A short animation showing how the gene expression of Hes5 in the developing mouse neural tube evolves over time and the migration of cells as they differentiate. There is an interactive simulation based on this tissue that you can find here.

The process of neurulation and the formation of the neural tube in the developing mouse embryo.

Idealised illustration of the structure of mouse neuroepithelial cells and how membrane protrusions relate to the experimentally measured cell widths.

Summary of the Sox2CreERT2 mTmG system used to mosaically label the membranes of neural progenitor cells in the neural tube.

An overview of Hes5 gene regulatory interactions and the corresponding cell-states. Used in seminar talks.

Schematic for a 2-cell mathematical model of Notch-Hes signalling.

Part of a figure from my most recent paper, specifically this shows the cellular structure of the neural tube.

Illustration from a figure in my most recent paper, showing how a simulated grid of cells maps onto a biological structure called the neural tube.

Where Hes5 is expressed within the developing neural tube. Taken from a figure in my most recent paper.

Figure that was made as part of a literature review to summarise the Notch-Hes5 signalling pathway.

A graphical abstract that I produced for a colleague's recent paper.

Seminar illustration of a gap-filling hypothesis mechanism that might operate during differentiation of neural stem cells in the developing spinal cord.

Illustration used in seminar talks that distinguishes between two cellular signalling distances.

Poster presented at the Theory of Living Matter conference in Cambridge 2019, which won a poster prize.